Mortality In Trauma Patients May Be Doubled By Old Red Blood Cells
Severe trauma patients requiring a major transfusion are twice as likely to die if they receive red blood cells stored for a month or longer, according to research published in BioMed Central's open access journal Critical Care.
Efficacy and Cost-Effectiveness of Cell Saving Blood Autotransfusion in Adult Lumbar Fusion
The objective of this study was to explore the use of cell saver blood autotransfusion in spinal surgery and to evaluate the efficacy and cost-effectiveness of cell saver blood autotransfusion during lumbar spine fusion in adults.
Impact of Fresh-Frozen Plasma from Male-Only Donors Versus Mixed-Sex Donors on Postoperative Respiratory Function in Surgical Patients: A Prospective Case-Control Study
: This study compared pulmonary function after the transfusion of FFP derived from either male donors only (FFP-male) or mixed donors (FFP-mixed) in informed surgical patients treated at a tertiary university hospital in Japan.
Does Blood Transfusion Harm Cardiac Surgery Patients?
Over recent years there has been a substantial body of evidence demonstrating strong associations between transfusion and adverse outcomes, including myocardial, neurological and renal injury, in a range of clinical settings where transfusion is administered for reasons other than life-threatening bleeding.
Lepirudin in the Management of Patients With Heparin-Induced Thrombocytopenia
Lepirudin, a recombinant hirudin, is a direct irreversible thrombin inhibitor by binding to both free and clot-bound thrombin.
Gaseous Microemboli in a Pediatric Bypass Circuit with an Unprimed Venous Line: An In Vitro Study
Miniaturizing cardiopulmonary bypass (CPB) circuits to reduce hemodilution and allogenic blood product administration is common in cardiac surgery.
An In Vitro Study of the Effectiveness of Carbon Dioxide Flushing of Arterial Line Filters
Gaseous microemboli (GMEs) have been connected to neurologic impairment and other ischemic complications after surgery.
Soluble Fibrin Monomer Complex and Cardiopulmonary Bypass
The purpose of this study was to determine whether a positive SFMC test is associated with pre-operative, intra-operative, and post-operative variables for patients that have undergone cardiopulmonary bypass (CPB).
Clinical Efficacy of Two-Phase Leukocyte Filtration in High-Risk Patients Undergoing Coronary Revascularization with Cardiopulmonary Bypass
The purpose of this study was to investigate the clinical outcome, inflammatory response and myocardial function in high-risk patients undergoing three different leukocyte depletion strategies.
Effects of Platelet-Rich Plasma on the Quality of Repair of Mechanically Induced Core Lesions in Equine Superficial Digital Flexor Tendons: A Placebo-Controlled Experimental Study
A placebo-controlled experimental trial was performed to test the hypothesis that a single intratendinous PRP treatment enhances the quality of tendon repair, as evidenced by improved biochemical, biomechanical, and histological tissue properties.
Blood Utilization at a Level I Trauma Center: Is This as Good as it Gets?
Recognition of the adverse effects of allogeneic blood resulted in the decreased use of red blood cell (RBC) transfusion in surgical practice in the 1990s.
Effects of Platelet-Rich Plasma on BMSCs Differentiation Into SC in Vitro
To explore effect of platelet-rich plasma (PRP) on rabbit BMSCs differentiation into SC in vitro and to detect secretory function of the differentiated cells.