The Relationship Among Thromboelastography, Hemostatic Variables, and Bleeding After Cardiopulmonary Bypass Surgery in Children
We aimed to (a) compare perioperative temporal profiles of TEG(R) and laboratory hemostatic variables between patients with significant hemorrhage (BLEED) and those without (CONTROL), (b) investigate the relationship between TEG(R) variables and routine hemostatic variables, and (c) develop a model for prediction of bleeding.
Heparin Dose Response Is Independent of Perioperative Antithrombin Activity in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Low Heparin Concentrations
We hypothesized that there would be a direct association between perioperative AT activity and both heparin dose response (HDR) and heparin sensitivity index (HSI) in patients undergoing coronary artery bypass graft surgery.
Preoperative Heparin Therapy Causes Immune-Mediated Hypotension Upon Heparin Administration for Cardiac Surgery
To evaluate whether patients with positive or negative heparin antibodies who received heparin preoperatively by continuous infusion developed cardiovascular changes upon heparin administration prior to cardiopulmonary bypass.
Predonation of Autologous Blood Reduces Perioperative Allogenic Transfusion Requirement In Grown-up Patients With Congenital Heart Disease
To investigate the efficacy of autologous blood predonation (ABP), we focussed on a homogeneous subgroup of patients, with right ventricular outflow tract reconstruction.
Meta-Analysis of Clinical Studies of the Purported Deleterious Effects of “Old” (Versus “Fresh”) Red Blood Cells: Are We at Equipoise?
A meta-analysis examined whether the available data support an adequate suspicion that transfusion of old red blood cells (RBCs) is associated with increased mortality, organ failure, infection, prolonged mechanical ventilation, and prolonged stay in the hospital or the intensive care unit.
The Inflammatory Response to Miniaturised Extracorporeal Circulation: A Review of the Literature
This review focuses on the inflammatory and clinical outcomes of using MECC and compares these to conventional cardio-pulmonary bypass (CCPB).
Hematocrit on Cardiopulmonary Bypass and Outcome After Coronary Surgery in Nontransfused Patients
This study aimed to identify the role of preoperative anemia and hemodilution during cardiopulmonary bypass as determinants of morbidity and mortality after coronary operations.
Blood Transfusion is Associated With Increased Morbidity and Mortality after Lower Extremity Revascularization
We queried the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database to examine the effect of intraoperative blood transfusion on the morbidity and mortality in patients who underwent lower extremity revascularization.
Argatroban as a Aubstitute of Heparin During Cardiopulmonary Bypass: A Safe Alternative?
The objective of this communication is to report our recent experience with this agent during cardiopulmonary bypass (CPB) and to review the cases previously published in order to better define indications, dosage, monitoring and limitations in cardiac surgery patients.
Microemboli in Our Bypass Circuits: A Contemporary Audit
We used the Emboli Detection and Classification quantifier (EDAC) (Luna Innovations, Roanoke, VA) in a prospective clinical audit of emboli in a contemporary CPB circuit.
Modified Ultrafiltration with the Hemobag (Video)
Scott Pacheco discusses his clinical experiences with the Hemobag at Palmetto Regional Hospital (27 minutes).
Duration of Red Blood Cell Storage and Outcomes in Pediatric Cardiac Surgery: An Association Found for Pump Prime Blood
The purpose of this study was to investigate the influence of red blood cell storage time prior to transfusion on postoperative morbidity in pediatric cardiac operations.