Changes in Mechanical Fragility and Free Hemoglobin Levels after Processing Salvaged Cardiopulmonary Bypass Circuit Blood with a Modified Ultrafiltration Device
This study evaluated the extent of hemolysis, the mechanical fragility index (MFI), and the amount of plasma free hemoglobin (PFHb) created after processing with the MUF device.
Ketamine as a Neuroprotective and Anti-Inflammatory Agent in Children Undergoing Surgery on Cardiopulmonary Bypass: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial
We hypothesized that ketamine, via N-methyl D-aspartate receptor blockade and anti-inflammatory effects, would reduce central nervous system injury during cardiopulmonary bypass.
Total Artificial Heart
In this review, we discuss the history of the TAH, its development and clinical application, implications for anaesthetic management, published outcomes and the future outlook for TAHs.
Coagulation Management in Patients Undergoing Mechanical Circulatory Support
The incidence of bleeding and thrombo-embolic complications in patients undergoing mechanical circulatory support therapy remains high and is associated with bad outcomes and increased costs.
Evaluation of Appropriate Serologic Testing for Suspected Heparin-Induced Thrombocytopenia
Purpose The predictive value of clinical "4-T's" scoring in patient selection for serologic testing to confirm suspected heparin-induced thrombocytopenia (HIT) was evaluated.
Characterizing the Impact of Minor Cannula Design Modification
The aim of this study was to investigate the effect of the internal diameter of the extracorporeal connecting tube of venous cannulas on flow rate (Q), pressure drop (delta P), and cannula resistance (delta P/Q²) values, using a computer assisted test bench.
Cerebral Microbleeds After Use of Extracorporeal Membrane Oxygenation in Children
We reviewed MRI scans for all vascular neurology consultations in children treated with ECMO at an academic medical center over a 5-year period.
Heart Rescue: The Role of Mechanical Circulatory Support in the Management of Severe Refractory Cardiogenic Shock
This article will review novel strategies in the management of cardiogenic shock including percutaneous MCS (intra-aortic balloon pump, Impella, TandemHeart, venoarterial extracorporeal membrane oxygenation) and surgically implanted devices (CentriMag) that are used for short-term management
Robotic-Assisted Endoscopic Atrial Septal Defect Closure: Analysis of 115 Cases in a Single Center
To summarize the experience with the application of robotic technique in totally endoscopic atrial septal defect closure in a single center
Device Thrombogenicity Emulation: A Novel Method for Optimizing Mechanical Circulatory Support Device Thromboresistance
To address the unmet need for enhancing the thromboresistance of these devices to extend their long term use, we developed a universal predictive methodology entitled Device Thrombogenicity Emulation (DTE) that facilitates optimizing the thrombogenic performance of any MCS device--ideally to a level that may obviate the need for mandatory anticoagulation.
Outcomes of Infants Weighing Three Kilograms or Less Requiring Extracorporeal Membrane Oxygenation After Cardiac Surgery
This single-center study investigated outcomes and risks for poor survival among infants weighing 3 kg or less.
Current Status of Mechanical Circulatory Support: a Systematic Review
This paper outlines the current status of mechanical circulatory support.