Point-of-Care Platelet Function Testing Predicts Bleeding in Patients Exposed to Clopidogrel Undergoing Coronary Artery Bypass Grafting: Verify Pre-Op TIMI 45–A Pilot Study
Guidelines recommend delaying coronary artery bypass grafting (CABG) for 5 days after discontinuing clopidogrel. However, platelet function may recover quicker in certain individuals.
Pre-Operative Anaemia
In this article, we review the incidence and impact of anaemia on the pre-operative patient. We explain how anaemia may be caused by functional iron deficiency, and how iron deficiency anaemia may be diagnosed and treated.
Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery
In this study the authors sought to determine the effect of tight intraoperative glucose control using a hyperinsulinemic-normoglycemic clamp approach on postoperative delirium in patients undergoing cardiac surgery.
How Can We Identify the High-Risk Patient
Accurate and early identification of high-risk surgical patients allows for targeted use of perioperative monitoring and interventions that may improve their outcomes. This review summarizes current evidence on how information from the preoperative, operative, and immediate postoperative periods can help identify such individuals.
Minimized Extracorporeal Circulation Does Not Impair Cognitive Brain Function After Coronary Artery Bypass Grafting
Objective evaluation of the impact of minimized extracorporeal circulation (MECC) on perioperative cognitive brain function in coronary artery bypass grafting (CABG) by electroencephalogram P300 wave event-related potentials and number connection test (NCT) as metrics of cognitive function.
Heart valve surgery in patients with homozygous sickle cell disease: A management strategy
Patients with the homozygous sickle cell disease have increased perioperative mortality. Some indications like heart valve surgery, may justify an exchange blood transfusion to reduce the proportion of hemoglobin S (HbS) and complications.
Effect of Respiratory Rehabilitation Before Open Cardiac Surgery on Respiratory Function: A Randomized Clinical Trial
The aim of this study was to evaluate the role of pulmonary rehabilitation before surgery for reducing the risk of pulmonary complications after surgery.
Diabetic Patients have Increased Perioperative Cardiac Risk in Heart-Type Fatty Acid-Binding Protein-Based Assessment
To test the potential role of heart-type fatty acid-binding protein (H-FABP) in detecting increased perioperative cardiac risk in comparison with cardiac troponin I (cTnI) in the early postoperative period.
Elevated Growth Differentiation Factor 15 Levels Predict Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) has emerged as a treatment of aortic stenosis in patients at high surgicalrisk. However, risk stratification in this elderly population is challenging, as patients at extreme risk might not benefit from TAVI.
Mechanisms of Oxidative Stress and Myocardial Protection During Open-Heart Surgery
In this article, we discuss the "deleterious" effects of the oxidative stress of the extracorporeal circulation and the up-to-date theories of "ideal'' myocardial protection.
Is There a Rationale for Short Cardioplegia Re-Dosing Intervals
While cardioplegia has been used on millions of patients during the last decades, the debate over the best technique is still going on.
High-Dose Polymerized Hemoglobin Fails to Alleviate Cardiac Ischemia/Reperfusion Injury Due to Induction of Oxidative Damage in Coronary Artery
This study was designed to investigate whether glutaraldehyde-polymerized human placenta hemoglobin (PolyPHb), a hemoglobin-based oxygen carrier (HBOC), can protect heart against cardiopulmonary bypass (CPB)-induced ischemia/reperfusion (I/R) injury or not and to elucidate the underlying mechanism.