CPB-Assisted Aortic Valve Replacement in a Pregnant 27-year-old with Endocarditis
A 27-year-old, G(3)P( 2)A(0) female with acute Staph aureus (SA) endocarditis successfully underwent CPB-assisted aortic valve replacement with a bioprosthetic aortic valve at 22 weeks' gestation.
Moderate Versus Deep Hypothermia for the Arterial Switch Operation–Experience with 100 Consecutive Patients
Evaluated the impact of moderate versus deep perioperative hypothermia on postoperative morbidity in patients receiving the arterial switch operation (ASO).
Acute Type II Aortic Dissection with Severe Aortic Regurgitation and Chronic Descending Aortic Dissection in Pregnant Patient with Marfan Syndrome
This case report involves a successful Bentall procedure for and recovery from a rare aortic dissection in a pregnant Marfan patient who developed acute type II aortic dissection with severe aortic regurgitation and chronic descending aortic dissection immediately after Cesarean section.
Emergency Tricuspid Valve Replacement During Pregnancy
High-flow (> 3.0 L/min(2)), high-pressure (> 70 mmHg), normothermic CPB using pulsatile flow and blood cardioplegia is thought to offer the best outcome to the fetus, although data to support these claims are not compelling.
Anaestheia for Valve Replacement in the Second Trimester of Pregnancy
The case is presented of a 19 weeks pregnant woman, who required a mitral valve replacement, which was achieved with success, and enabled her to complete her pregnancy without complications. Details are provided on the published references on which our management was based.
Perioperative Coagulation Management During Cardiac Surgery
Prospective randomized multicenter studies are needed to confirm the hypothesis that algorithm-based specific hemotherapy in conjunction with POC testing minimizes patient's exposure to blood products and improves clinical outcome.
The Future:Therapy of Myocardial Protection
Recent studies have proposed that old, inexpensive drugs--in human use for decades (e.g., β-blockers and cyclosporine, among others)--can reduce ischemia/reperfusion injury, I/R injury, when administered intravenously before coronary opening. The demonstration of such a cardioprotective effect should have a significant impact in the care of AMI patients.
Off-Pump Coronary Artery Bypass Grafting–The Current State
The benefits of OPCAB techniques may be more apparent for patients at high risk for complications associated with CPB and aortic manipulation. Recent studies have demonstrated improved outcomes in higher-risk patients undergoing OPCAB, as well as improved neurological outcomes. The purpose of this review is to outline the recent literature comparing OPCAB with ONCAB, and to demonstrate efficacy of OPCAB as a useful technique for coronary revascularization.
Cyclosporine A Normalizes Mitochondrial Coupling, Reactive Oxygen Species Production, and Inflammation and Partially Restores Skeletal Muscle Maximal Oxidative Capacity in Experimental Aortic Cross-Clamping
Cyclosporine A normalized ROS production, decreased inflammation, and restored mitochondrial coupling during aortic cross-clamping. Incomplete V(max) protection might be due to low cyclophilin D expression in gastrocnemius, preventing CsA from blocking mPTP opening.
Right Atrial Myxoma and Severe Left Ventricular Dysfunction: Which Explanations? Which Management?
A 57 year-old woman with a large right atrial myxoma underwent emergency surgical resection in our institute. It is known that surgical management of such tumours is difficult regarding venous cannulation and embolic risk, but in our patient, the surgery was more challenging because of the severe left ventricular dysfunction.
Diabetes Clinical Trials: Helped or Hindered by the Current Shift in Regulatory Requirements
The potential for some agents to increase the risk of cardiovascular events has led to substantial changes in regulatory requirements for new anti-diabetic therapies. These requirements, while key to ensuring the cardiovascular safety of new agents, fail to emphasize the need to show clinical benefits, such as less visual impairment, less need for dialysis, or fewer cardiovascular events and deaths.
Left-Right Ventricular Interactions in Pediatric Aortic Stenosis: Right Ventricular Myocardial Strain Before and After Aortic Valvuloplasty
Ventricular-ventricular interactions may affect left ventricular (LV) and right ventricular (RV) function but have not been well characterized in chronic LV afterload in children. The aim of this study was to assess RV myocardial strain in children with aortic stenosis before and after aortic balloon valvuloplasty.