Low Hemorrhage-Related Mortality in Trauma Patients in a Level I Trauma Center Employing Transfusion Packages and Early Thromboelastography-Directed Hemostatic Resuscitation with Plasma and Platelets
This was a prospective study of adult trauma patients admitted to a Level I trauma center. Demography, Injury Severity Score (ISS), transfusion therapy, and mortality were registered. Hemostatic resuscitation was based on a massive transfusion protocol encompassing transfusion packages and thromboelastography (TEG)-guided therapy.
Combination Therapy of Human Adipose-Derived Stem Cells and Basic Fibroblast Growth Factor Hydrogel in Muscle Regeneration
In this study, we determined whether the combination therapy using human adipose-derived stem cells (h-ADSCs) and basic fibroblast growth factor (bFGF) incorporated into hydrogel could enhance muscle regeneration in a muscle laceration animal model.
Influence of Tranexamic Acid on Postoperative Autologous Blood Retransfusion in Primary Total Hip and Knee Arthroplasty: A Randomized Controlled Trial
In this study, we hypothesized that adding tranexamic acid (TXA) to a restrictive blood transfusion protocol would reduce the need for postoperative autologous blood retransfusion in primary knee and hip arthroplasty.
PHD2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium
We studied if and how Prolyl hydroxylase domain protein 2 silencing in human adipose-derived stem cells (ADSCs) enhances their cardioprotective effects after transplantation into infarcted hearts.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
This study seeks to establish if processing residual CPB volume with ultrafiltration reduces homologous blood transfusion and bleeding.
Diagnosis and Management of Primary Aldosteronism: An Updated Review
Utilizing a physician-centered approach, we intend to provide up-dated information on the etiology, diagnosis, and the management of Primary Aldosteronism.
Open Aortic Valve Replacement in a Patient with Glanzmann’s Thrombasthenia: A Multidisciplinary Strategy to Minimize Perioperative Bleeding
Patients with GT requiring cardiac surgical procedures are at high risk for perioperative bleeding complications. This case report illustrates the importance of multidisciplinary planning, TEG analysis, and the judicious use of recombinant factors to minimize operative bleeding risk.
The Relationship Between Fibrinogen Levels After Cardiopulmonary Bypass and Large Volume Red Cell Transfusion in Cardiac Surgery: An Observational Study
The relationship between post-CPB fibrinogen levels and large volume red cell transfusion was explored in this study.
Earlier Detection of Coagulopathy with Thromboelastometry During Pediatric Cardiac Surgery: A Prospective Observational Study
This study helps to determine whether thromboelastometry (TEM) analysis before weaning from cardiopulmonary bypass (CPB) and hemoconcentration is predictive of post-CPB results and whether analysis of clot firmness already after 10 min yields reliable results.
Novel Ultrafiltration Technique for Blood Conservation in Cardiac Operations
The performance characteristics and clinical outcome of a novel hemoconcentrator, the HemoSep (Brightwake, Nottingham, United Kingdom), for reusing salvaged blood postoperatively were evaluated.
Zero Balance Ultrafiltration for the Correction of Acute Acidosis after a Period of Prolonged Deep Hypothermic Circulatory Arrest
Our case illustrates that Z-BUF offers a valuable option for the correction of severe electrolyte and acid-base disturbances in adults undergoingcardiac surgery.
Evaluation of Coagulation Factors and Platelet Function from an Off-Line Modified Ultrafiltration Technique for Post-Cardiopulmonary Bypass Circuit Blood Recovery
This study evaluated the off-line MUFprocess of the Hemobag (HB, Global Blood Resources, Somers, CT, USA) to quantitate coagulation factor levels, platelet (PLT) count and function in one facility and cellular growth factor concentrations of the final product that were transfused to the patient in another facility