A Strong Regenerative Ability of Cardiac Stem Cells Derived from Neonatal Hearts
We hypothesized that isolated neonatal-derived cardiac stem cells (CSCs) may have a higher regenerative ability than adult-derived CSCs and might address the structural deficiencies of congenital heart disease.
Characterization and functionality of cardiac progenitor cells in congenital heart patients
Human cardiac progenitor cells (hCPCs) may promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of hCPCs in young patients with nonischemic congenital heart defects for potential use in congenital heart defect repair warrants exploration.
Potential for Stem Cell Use in Congenital Heart Disease
This article reports on the evolving field of stem cell therapy and its impact on the management of cardiac pathology, in particular congenital heartdisease.
Shovel-Ready’ Applications of Stem Cell Advances for Pediatric Heart Disease
This review will focus on two advances in basic science that are now translating into clinical trials.
Monitoring Incomplete Heparin Reversal and Heparin Rebound After Cardiac Surgery
To assess the incidence of incomplete heparin reversal and heparin rebound after cardiac surgery with cardiopulmonary bypass (CPB) and the ability of the activated coagulation time (ACT) and thromboelastography (TEG) to detect these phenomena.
Results with an Anticoagulation Protocol in 99 SynCardia Total Artificial Heart Recipients
For 15 years, we employed a consistent anticoagulation protocol in 99 consecutive SynCardia Systems total artificial heart (TAH) recipients.
Mini-Extracorporeal Circulation Minimizes Coagulation Abnormalities and Ameliorates Pulmonary Outcome in Coronary Artery Bypass Grafting Surgery
Hemostasis is impaired during CABG and coagulation abnormalities often result in clinically relevant organ dysfunctions, eventually increasing morbidity and mortality rates.
Management of Patients with Hematological Malignancies Undergoing Coronary Artery Bypass Grafting
We describe three cases with hematological malignancies namely chronic myelogenous leukemia, acute promyelocytic leukemia and chronic lymphocytic leukemia presenting for coronary artery bypass grafting (CABG).
Myocardial Damage Following Cardiac Surgery: Comparison Between Single-Dose Celsior Cardioplegic Solution and Cold Blood Multi-Dose Cardioplegia
The aim of this study was to assess myocardial damage after heart valve surgery performed with myocardial protection of a single dose of Celsior cardioplegia or with repeated cold blood cardioplegia.
Use of del Nido Cardioplegia Solution and a Low-Prime Recirculating Cardioplegia Circuit in Pediatrics
Our institution has modified a low-prime cardioplegia system (CPS) and adopted a single-dose cardioplegia solution (del Nido cardioplegia) for our congenital heart disease population. The goal of this article is to describe our CPS and outline our myocardial protection protocol.
Postoperative Cardiac Damage after Standardized Carotid Endarterectomy Procedures in Low- and High-Risk Patients
We conducted a comparison of postoperative cardiac damage, defined as cardiac troponin I (cTn-I) elevation, after carotid endarterectomy in low- and high-risk patients.
Effect of Remote Ischemic Preconditioning on Phosphorylated Protein Signaling in Children Undergoing Tetralogy of Fallot Repair: A Randomized Controlled Trial
Our previous randomized controlled trial demonstrated cardiorespiratory protection by remote ischemic preconditioning (RIPC) in children before cardiac surgery. However, the impact of RIPC on myocardial prosurvival intracellular signaling remains unknown in cyanosis.