Microbubble Transmission during Cardiotomy Infusion of a Hardshell Venous Reservoir with Integrated Cardiotomy versus a Softshell Venous Reservoir with Separated Cardiotomy: An In Vitro Comparison
The purpose of this study was to compare the Medtronic IC-HSVR (Affinity NT CVR) with Medtronic’s SC-SSVR (CB 1351, CBMVR 1600) in terms of relative microbubble transmission during cardiotomy infusion.
The Thoratec® CentriMag® for Pediatric Right Ventricular Failure
We describe the successful use of the Thoratec® CentriMag® in a pediatric patient posttransplantation with acute right ventricular failure.
The Effects of Pressure on Gases in Solution: Possible Insights to Improve Microbubble Filtration for Extracorporeal Circulation
Improvements in micropore arterial line filter designs used for extracorporeal circulation are still needed because microbubbles larger than the rated pore sizes are being detected beyond the filter outlet.
Preoperative Statin Therapy in Cardiac Surgery is More Effective in Patients Who Display Preoperative Activation of the Inflammatory System
We sought to determine whether preoperative statin treatment is more effective in reducing, after cardiac surgery with cardiopulmonary bypass, systemic inflammatory response and myocardial damage markers in patients who have elevated preoperative interleukin-6 levels than in patients who have normal preoperative interleukin-6 levels.
Rationale and Design of the Investigation of the Management of Pericarditis (IMPI) Trial: a 2 × 2 Factorial Randomized Double-Blind Multicenter Trial of Adjunctive Prednisolone and Mycobacterium with Immunotherapy in Tuberculous Pericarditis
The primary objective of the IMPI Trial is to assess the effectiveness and safety of prednisolone and M. w immunotherapy in reducing the composite outcome of death, constriction, or cardiac tamponade requiring pericardial drainage in 1,400 patients with TB pericardial effusion.
From Bloodless Surgery to Patient Blood Management
Patient blood management strategies can be applied at every stage of care to surgical and nonsurgical patients, and they generally fall under one of these three categories (the so-called pillars of blood management): optimizing hematopoiesis and appropriate management of anemia, minimizing bleeding and blood loss, and harnessing and optimizing physiological tolerance of anemia through employing all available modalities while treatment is initiated.
Effect of an Investigational Vaccine for Preventing Staphylococcus Aureus Infections after Cardiothoracic Surgery: A Randomized Trial
This study evaluates the efficacy and safety of preoperative vaccination in preventing serious postoperative S. aureus infection in patients undergoing cardiothoracic surgery.
Orthotopic Replacement of Aortic Heart Valves with Tissue-Engineered Grafts
This study presents the function and morphological changes of a tissue-engineered aortic valve (TEV) compared to the cryopreserved valve (CPV), aortic valve (AV) allografts in an orthotopic position in sheep.
Blood Substitutes: Evolution from Non Carrying to Oxygen-and Gas-Carrying Fluids
The development of oxygen (O2)-carrying blood substitutes has evolved from the goal of replicating blood O2 transport properties to that of preserving microvascular and organ function, reducing the inherent or potential toxicity of the material used to carry O2, and treating pathologies initiated by anemia and hypoxia.
Cardiovascular Tissue Engineering Research Support at the National Heart, Lung, and Blood Institute
This article is a review of the tissue engineering programs of the National Heart, Lung, and Blood Institute, which support research efforts to translate novel approaches for the treatment of cardiovascular disease.
Fabrication of Small-Diameter Vascular Scaffolds by Heparin-Bonded P(LLA-CL) Composite Nanofibers to Improve Graft Patency
The poor patency rate following small-diameter vascular grafting remains a major hurdle for the widespread clinical application of artificial bloodvessels to date.
The Approach to Patients with Bleeding Disorders Who Do Not Accept Blood-Derived Products
Despite the widespread use of allogeneic blood components in clinical practice, there are patients in whom transfusion cannot be carried out for various reasons, including refusal of transfusions because of religious beliefs.