Successful Anticoagulation with Fresh Frozen Plasma for Cardiopulmonary Bypass in a Patient with Heparin Resistance: A Cautionary Tale
We report a case of successful anticoagulation with the intraoperative administration of fresh frozen plasma in a high-risk coronary patient with HR and highlight the perils of unwitting overheparinisation in such cases.
Potential Biomarkers for Predicting Outcomes in CABG Cardiothoracic Surgeries
In this review, we assess currently available cardiac biomarkers as predictors of clinical outcome for post-operative CABG patients.
Apnea Test for Brain Death Determination in a Patient on Extracorporeal Membrane Oxygenation
Apnea test is a key component to confirm brain death. For patients receiving extracorporeal membrane oxygenation (ECMO), apnea test remains challenging. Brain death (BD) diagnosis is often made without apnea test.
Do Interleukin-10 and Superoxide Ions Predict Outcomes of Cardiac Extracorporeal Membrane Oxygenation Patients?
Our observations lead to the hypothesis that a proper response to cardiogenic shock by releasing the appropriate amount of IL-10 is required for survival in the cases of AMI and DCMP. For myocarditis, proper responses in IL-10 and superoxide ions are needed.
Protamine Overdose and Its Impact on Coagulation, Bleeding, and Transfusions After Cardiopulmonary Bypass: Results of a Randomized Double-Blind Controlled Pilot Study
We assessed the effects of protamine overdosing on thrombelastometry, bleeding, and transfusions in patients after cardiopulmonary bypass (CPB).
Antithrombin Activity and Outcomes in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
Our results confirm the role of low postsurgery AT activity influencing outcomes in patients undergoing CPB.
Effect of Air Exposure and Suction on Blood Cell Activation and Hemolysis in an In Vitro Cardiotomy Suction Model
A study was designed to describe the effects of both suction and an air-blood interface independently and in combination on leukocyte and platelet activation, and hemolysis in an in vitro model.
Long-Term Results of Dialysis Patients with Chronic Kidney Disease Undergoing Coronary Artery Bypass Grafting
The present study suggested that surgical outcome of CABG in dialysis patients was not satisfactory.
The Relationship between Fibrinogen Levels after Cardiopulmonary Bypass and Large Volume Red Cell Transfusion in Cardiac Surgery: An Observational Study
We explored the relationship between post-CPB fibrinogen levels and large volume red cell transfusion.
Crystalloids vs. Colloids: KO at the Twelfth Round?
The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported.
Managing the Extracorporeal Membrane Oxygenation (ECMO) Circuit Integrity and Safety Utilizing the Perfusionist as the “ECMO Specialist”
We have now developed a safe circuit and fiscally responsible staffing model that utilizes a perfusionist and a telemetry-based electronic record keeper, permitting the perfusionist to leave the bedside and interact with the circuit when necessary.
Is Elimination of Cardiotomy Suction Preferable in Aortic Valve Replacement? Assessment of Perioperative Coagulation, Fibrinolysis and Inflammation
Guidelines recommend the avoidance of direct return of pericardial blood based on evidence from coronary surgery.