Overview of the 2012 Food and Drug Administration Circulatory System Devices Panel Meeting on the Reclassification of External Counterpulsation, Intra-Aortic Balloon Pump, and Non-Roller-Type Cardiopulmonary Bypass Blood Pump Devices
The Food and Drug Administration held a Circulatory System Devices Advisory Panel meeting,
Unexpected Abrupt Increase in Left Ventricular Assist Device Thrombosis
We investigated the occurrence of pump thrombosis and elevated lactate dehydrogenase (LDH) levels, LDH levels presaging thrombosis (and associated hemolysis), and outcomes of different management strategies in a multi-institutional study.
Leukocyte Depletion During CPB: Effects on Inflammation and Lung Function
The aim of this study was to evaluate the effects of CPB leukocyte filtration on inflammation and lung function after coronary artery bypass grafting (CABG).
Impact of Cold Ischemia on Mitochondrial Function in Porcine Hearts and Blood Vessels
The effects of cold storage using Custodiol® (Histidine-Tryptophan-Ketoglutarate, HTK) or isotonic saline solution on mitochondrial function in hearts (left and rights ventricles) and various blood vessels of pigs were investigated.
Cardioprotection with Esmolol Cardioplegia: Efficacy as a Blood-Based Solution
An esmolol-based cardioplegic solution may be a beneficial alternative to hyperkalaemic solutions.
The Impact of Crystalloidal and Colloidal Infusion Preparations on Coronary Vascular Integrity, Interstitial Oedema and Cardiac Performance in Isolated Hearts
It appears important to maintain the pH value within a physiological range to maintain optimal myocardial contractility.
Treatment of Knee Chondropathy with Platelet Rich Plasma. Preliminary Results at 6 Months of Follow-Up with Only One Injection
Recently, PRP have been used to treat early moderate chondropathies. Here we show the preliminary results of 30 patients affected by chondropathy of the knee after 6 months treated with a single intrarticular injection of PRP.
Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement
The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that among high-risk patients with aortic stenosis, the 1-year survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical replacement.
High Technology in Medicine: Lessons from Cardiovascular Innovations and Future Perspective
Four decades of innovations in the field of interventional cardiology are presented as an example for the great growth of high technology in medicine, side by side with the development of general technology and science.
Autologous Bone Marrow Concentrate: Review and Application of a Novel Intra-Articular Orthobiologic for Cartilage Disease
The potential of cell-based orthobiologic injection therapies (pertaining to therapeutic injectables that aim to restore the biologic environment and/or structural components of diseased or damaged musculoskeletal tissue) is of tremendous interest for younger, more active patients, and is even more appealing in that such therapy can be delivered at point-of-care in the clinic during an office visit.
Acute Mesenteric Ischemia after Cardiac Surgery: An Analysis of 52 Patients
The aim of this retrospective study was to evaluate the incidence, outcome, and perioperative risk factors of AMI in the patients undergoing elective cardiac surgery.
Will Catheter Interventions Replace Surgery for Valve Abnormalities
This review aims to summarize the current state-of-the-art for transcatheter valve replacement (TVR) in congenital heart disease (CHD); the expanding indications for TVR; and the technological obstacles to optimizing TVR.