Hemodilution During Cardiopulmonary Bypass Increases Cerebral Infarct Volume After Middle Cerebral Artery Occlusion in Rats
Hemodilution (hemoglobin, 6 g/dL) increased cerebral infarct volume and worsened outcome after focal cerebral ischemia during cardiopulmonary bypass in rats; this suggests that excessive hemodilution may increase the risk of cardiac surgery-related stroke.
Extracorporeal Elimination of Large Concentrations of Tirofiban by Zero-Balanced Ultrafiltration During Cardiopulmonary Bypass: An In Vitro Investigation
Our data provide evidence that ultrafiltration is an effective method for extracorporeal elimination of high therapeutic levels of tirofiban.
Does Off-Pump Coronary Artery Bypass Reduce the Incidence of Clinically Evident Renal Dysfunction After Multivessel Myocardial Revascularization?
This prospective, observational trial suggests that patients who undergo complete coronary revascularization without cardiopulmonary bypass (off-pump) have similar incidences of postoperative creatinine increases when compared with patients undergoing traditional coronary artery bypass surgery with cardiopulmonary bypass.
Current Status of Blood Component Therapy in Surgical Critical Care
Current data regarding blood transfusion thresholds and risks of blood transfusion have not as yet significantly altered practice patterns.
Antiplatelet Therapy and Blood Transfusions in Coronary Surgery with CPB
This study suggests consideration should be given to delaying elective CABG for patients who have received APT treatment until APT is discontinued for at least 5 days.
Coronary Revascularization Outcomes Have Improved in Elderly Patients
A multicenter analysis of data from more than 200,000 adults who underwent percutaneous coronary intervention or coronary artery bypass grafting shows that over the last decade the use of these techniques in elderly patients has increased and their outcomes have improved.
Complement Suppression Drug Does Not Prevent Cognitive Decline After CABG
Treatment with pexelizumab, a monoclonal antibody against the C5 complement component, does not prevent the overall drop in cognition that can occur after coronary artery bypass grafting (CABG), new research shows.
Florida Program Aims to Attract More Men to Nursing Profession
In an attempt to alleviate the nursing shortage in Florida, the Florida Nursing Students Association recently launched a campaign to attract more […]
Plasma-Modified ACT Can Be Used to Monitor Bivalirudin (Angiomax) Anticoagulation for On-Pump Cardiopulmonary Bypass Surgery in a Patient with Heparin-Induced Thrombocytopenia
We report here the successful use of bivalirudin anticoagulation on pump, with no additional morbidity, and the first reported use of the plasma-modified ACT (activated clotting time) test, a simple modification of the standard ACT assay, to monitor the anticoagulant effect of bivalirudin.
North American Neonatal Extracorporeal Membrane Oxygenation (ECMO) Devices: 2002 Survey Results
When compared to a 1990 survey, a shift away from using bladder boxes and toward using air bubble detectors is apparent. But other than those two shifts, ECMO is done in much the same manner as it was done 12 years ago.
Effect of Cardiopulmonary Bypass on Cortical Cerebral Oxygenation During Coronary Artery Bypass Grafting
Conventional CABG is responsible for deterioration in [O2Hb], and CBV, which peak at 40–60 min following initiation of CPB. The changes in [O2Hb] are reversible whereas the reduction of CBV persists to the end of the surgery.
Muscular Counterpulsation: Preliminary Results of a Non-Invasive Alternative to Intra-Aortic Balloon Pump
MCP and IABP had the same effects on CO and LVSWI. Moreover, MCP reduced SVR and increased the peripheral circulation without requiring any vascular access nor anticoagulation therapy.