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Management of Anticoagulation and Hemostasis for Pediatric Extracorporeal Membrane Oxygenation
Compared to in situ vascular physiology where pro and anti-hemostatic processes are in balance to maintain hemostasis, the use of ECMO in a critically ill child increases the risk of hemorrhagic or thromboembolic events due to a perturbation in the balance inherent of this complex system.
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Ross Ungerleider discuss provides an abstract perspective on demystifying dogma in order to create progress.
Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis
Based on the pooled results of the available literature, RAP is associated with a significant reduction in intraoperative and whole hospital allogeneic red cell transfusion. Use of RAP may prevent hemodilution of cardiac surgical patients and thus, lessen transfusions. Additional high-quality prospective studies are necessary to determine the ideal priming volume necessary to confer the greatest benefit without incurring organ injury.
