Patient Blood Management In The Cardiac Surgical Setting: An Updated Overview
In cardiac surgical patients it is a complex challenge to find the ideal balance between anticoagulation and hemostasis. Preoperative anemia and perioperative higher transfusion rates are related to increased morbidity and mortality. Patient blood management (PBM) is an evidence based patient specific individualized protocol used in the perioperative setting in order to reduce perioperative bleeding and transfusion rates and to improve patient outcomes.
The Influence Of Gaseous Microemboli On Various Biomarkers After Minimized Cardiopulmonary Bypass
Gaseous microemboli that originate from the cardiopulmonary bypass circuit may contribute to adverse outcome after cardiac surgery. We prospectively evaluated the influence of gaseous microemboli on the release of various biomarkers after use of a minimally invasive extracorporeal technology system.
Intraoperative Mechanical Ventilation And Postoperative Pulmonary Complications After Cardiac Surgery
In this retrospective analysis, the intraoperative ventilation bundle was associated with a lower rate of postoperative pulmonary complicationsLower modified driving pressure was independently associated with fewer pulmonary complications BACKGROUND:: Compared with historic ventilation strategies, modern lung-protective ventilation includes lower tidal volumes (VT), lower driving pressures, and application of positive end-expiratory pressure (PEEP). The contributions of each component to an overall intraoperative protective ventilation strategy aimed at reducing postoperative pulmonary complications have neither been adequately resolved, nor comprehensively evaluated within an adult cardiac surgical population.
Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review
The substantial growth over the last decade in the use of extracorporeal life support for adults with acute respiratory failure reveals an enthusiasm for the technology not always consistent with the evidence. However, recent high-quality data, primarily in patients with acute respiratory distress syndrome, have made extracorporeal life support more widely accepted in clinical practice.
Patient Blood Management Is Not About Blood Transfusion: It Is About Patients’ Outcomes
Patient Blood Management (PBM) is "the timely application of evidence-based medical and surgical concepts designed to maintain hemoglobin concentration, optimize hemostasis and minimize blood loss in an effort to improve patient outcome".
Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement
In patients undergoing aortic-valve or mitral-valve replacement, either a mechanical or biologic prosthesis is used. Biologic prostheses have been increasingly favored despite limited evidence supporting this practice.
Mitral Valve Repair: Moving Towards a Personalized Ring
Abstract BACKGROUND: Mitral valve repair with the use of an annuloplasty ring is the procedure of choice in patients with significant mitralregurgitation (MR) due to floppy mitral […]
Interim Results of the 5-Box Thoracoscopic Maze Procedure
Using a totally thoracoscopic approach, isolation of all left atrial arrhythmogenic substrate is achieved through the creation of 5 discrete but contiguous compartments, thereby enabling unambiguous verification with bidirectional block
Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear.
Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery
We performed a patient-level combined analysis of randomized, controlled trials to compare radial-artery grafts and saphenous-vein grafts for coronary-artery bypass grafting (CABG).
Calculating Risk for Poor Outcomes After Transcatheter Aortic Valve Replacement
The object of this study is to outline the tools available to help understand the risk of transcatheter aortic valve replacement (TAVR) and the gaps in knowledge regarding TAVR risk estimation.
Venous-to-Arterial pCO2 Difference in High-risk Surgical Patients
Alteration of tissue perfusion is a main contributor to organ dysfunction in high-risk surgical patients. The difference between venous carbon dioxide and arterial carbon dioxide pressure (pCO2 gap) has been described as a parameter reflecting tissue hypoperfusion in critically ill patients who are insufficiently resuscitated.