Initial ELSO Guidance Document ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure
The Extracorporeal Life Support Organization (ELSO) and all of the ELSO worldwide chapters have prepared this document to describe when and how to use extracorporeal membrane oxygenation (ECMO) in COVID-19 patients during this pandemic.
Coronaviruses and the Cardiovascular System: Acute and Long-Term Implications
The present COVID-19 outbreak emphasizes the need for greater awareness of the immediate and long-term cardiovascular implications of viral infection and the significant gaps in knowledge that future research will need to address.
Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease
Despite ACE2 serving as the portal for infection, the role of ACE inhibitors or angiotensin receptor blockers requires further investigation. COVID-19 poses a challenge for heart transplantation, impacting donor selection, immunosuppression, and post-transplant management.
Covid-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome
Relatively high compliance indicates well preserved lung gas volume in this patient cohort, in sharp contrast to expectations for severe ARDS.
Effect of Intra-arterial Nimodipine on Cerebral Oxygen Saturation and Systemic Hemodynamic Indices in Patients With Cerebral Vasospasm: A Prospective Cohort Study
IaN for aSAH-related cerebral vasospasm did not improve rScO2 but was associated with significant systemic hemodynamic effects, including a decrease in MBP and TPRI. These hemodynamic changes might offset any potential effects of IaN to improve rScO2.
Platelet Function Analysed by ROTEM Platelet in Cardiac Surgery after Cardiopulmonary Bypass and Platelet Transfusion
ROTEM platelet with thrombin activation, TRAP‐tem, improved significantly, indicating that platelet transfusion may reverse cardiopulmonary bypass‐induced platelet dysfunction.
Cell-Cycle Arrest Biomarkers Usefulness for Cardiac Surgery-Related Acute Kidney Injury in Neonates and Infants
These findings question the usefulness of (TIMP-1) × (IGFBP-7) for the prediction of cardiac surgery-related acute kidney injury in neonates and infants when measured within 3 hours of cardiopulmonary bypass.
Increased Circulating Levels of Neutrophil Extracellular Traps During Cardiopulmonary Bypass
Circulating NETs measurements increases during cardiac surgery with postsurgical levels proportional to CPB duration. The clinical significance of NETs production during cardiac surgery should be further investigated.
The Relationship Between Neurocognitive Decline and the Heart‐Lung Machine
Further research, comparing on‐pump and off‐pump cohorts and involving intensive screening of preoperative cognitive decline, is indicated to elucidate the true neurocognitive consequences of the heart‐lung machine.
ECMO for COVID19 in Japan
Current situation of ECMO use in Japan for COVID-19 associated ARDS: second ELSO webinar focused on the use of ECLS during the SARS-CoV-2 pandemics, run on March 30th.
ECMO in COVID19: The Power of Connection
The power of connection: at a time when social distancing is a universal necessity, connecting as a healthcare community has never been so vitally important to keeping our patients & colleagues safe.
Sourcing Personal Protective Equipment During the COVID-19 Pandemic
An increase in PPE supply in response to this new demand will require a large increase in PPE manufacturing, a process that will take time many health care systems do not have, given the rapid increase in ill COVID-19 patients.