COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Herein, we review the current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexisting thrombotic disease who develop COVID-19, or those who need prevention or care for their thrombotic disease during the COVID-19 pandemic.
COVID-19 Respiratory Failure: Targeting Inflammation on VV-ECMO Support
We present the first successful case of VV-ECMO support to recovery of COVID-19 respiratory failure in North America.
Novel Percutaneous Dual-Lumen Cannula-Based Right Ventricular Assist Device Provides Effective Support for Refractory Right Ventricular Failure after Left Ventricular Assist Device Implantation
The use of the Protek Duo as a percutaneous RVAD is a safe and feasible treatment for patients who develop acute right heart failure after LVAD implantation.
Aortic Calcifications on Routine Preoperative Chest X-ray and Perioperative Stroke During Cardiac Surgery: a Nested Matched Case–Control Study
In our study population, CXR findings on aortic calcification were not related to the risk of embolic stroke.
Heparin-Induced Thrombocytopenia in Patients Undergoing Valvular and Aortic Surgery: A Modern Assessment of Risk
Patients who developed HIT after non-CABG cardiac surgery experienced increased postoperative rates of morbidity and mortality.
The Physiology of Oxygen Transport by the Cardiovascular System: Evolution of Knowledge
The authors describe how religious and cultural constraints, as well as superstition-based medical traditions, at times impeded experimentation and the acquisition of knowledge related to O2 transport.
Intraoperative Optimization of Both Depth of Anesthesia and Cerebral Oxygenation in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery—A Randomized Controlled Pilot Trial
This pilot trial demonstrates that noninvasive target-controlled depth of anesthesia monitoring is feasible. Cognitive function at 6 weeks showed no difference between the treatment and control groups; however, postoperative delirium was reduced in the intervention group.
A Comparison of the Arterial Blood Concentration of Isoflurane During Cardiopulmonary Bypass Between 2 Polypropylene Oxygenators
No significant difference in arterial blood concentration of isoflurane or BIS was found between the Inspire 8F (Sorin) and Affinity Fusion (Medtronic) oxygenators.
The Conundrum and Opportunity of Gender Equity For Evidence Generators
Collectively, all stakeholders must take responsibility for promoting equity in academic medicine because a diverse and inclusive medical workforce will generate the best possible evidence and result in a more innovative, high-performing, and ultimately, successful scientific enterprise.
Severe Vasoplegic Shock During Coronary Artery Bypass Surgery: Therapeutic challenges and Dilemmas in Hemodynamic Rescue
Herein a case of severe vasoplegia after coronary artery bypass surgery with cardiopulmonary bypass that was refractory to catecholamines and vasopressin is presented.
The Impact of Cardiopulmonary Bypass Management on Outcome: a Propensity Matched Comparison Between Minimally Invasive and Conventional Valve Surgery
This study showed that increasing the haemoglobin level might be helpful to reduce the incidence of cardiac surgery-associated acute kidney injury after minimally invasive mitral valve surgery.