COVID-19 and ECMO: the Interplay Between Coagulation and Inflammation—a Narrative Review
The present review summarizes the evidence on ECMO management of severe ARDS in light of recent COVID-19 pandemic, at the same time focusing on differences and similarities between SARS-CoV-2 and ECMO in terms of hematological and inflammatory interplay when these two settings merge.
Should COVID-19 Take Advice from Rheumatologists?
Although the degree and extent of systemic inflammation seen in patients with COVID-19 is typically less than in haemophagocytic lymphohistocytosis and macrophage activation syndrome, many observational studies have identified associations between inflammatory biomarkers
COVID-19 in Cardiac Surgery: A Proposed Prioritization Framework
A prioritization framework based on already published risks scores and guidelines for appropriate use are described as an added tool to supplement thorough patient assessment and sound clinical judgment.
Association of Treatment Dose Anticoagulation with In-Hospital Survival Among Hospitalized Patients with COVID-19
We assessed association between administration of in-hospital AC and survival in a large cohort of hospitalized patients with COVID-19.
High Risk of Thrombosis in Patients with Severe SARS-CoV-2 Infection: a Multicenter Prospective Cohort Study
Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore probably be suggested.
Safe Reintroduction of Cardiovascular Services during the COVID-19 Pandemic: Guidance from North American Society Leadership
As regions move along the journey of managing the COVID-19 pandemic, there is an opportunity to reintroduce regular cardiovascular care in a progressive manner with appropriate safeguards.
Adult Cardiac Surgery and the COVID-19 Pandemic: Aggressive Infection Mitigation Strategies are Necessary in the Operating Room and Surgical Recovery
These are guidance recommendations during a pandemic surge to be utilized for ALL patients while local COVID-19 disease burden remains elevated.
Clinical and Laboratory Predictors of In-Hospital Mortality in Patients with COVID-19: a Cohort Study in Wuhan, China
We developed two predictive models for the in-hospital mortality of patients with COVID-19 in Wuhan and validated in patients from another center.
Anesthesia and COVID-19: What We Should Know and What We Should Do
Through a comprehensive review of existing studies on COVID-19, this article presents the epidemiological and clinical characteristics of COVID-19, reviews current medical management, and suggests ways to improve the safety of anesthetic procedures.
Mechanical Circulatory Support with the Impella® LP5.0 Pump and an Intra-Aortic Balloon Pump for Cardiogenic Shock in Acute Myocardial Infarction: The IMPELLA-STIC Randomized Study
In patients with CS-AMI stabilized by initial treatment with inotropes and an IABP, the Impella LP5.0 did not provide additional haemodynamic support or improvement in LVEF at 1 month; its use in this setting might be futile and possibly harmful.
Multi-Modal Characterization of the Coagulopathy Associated With Extracorporeal Membrane Oxygenation
Therapy protocols for treating extracorporeal membrane oxygenation-associated coagulopathy should be further validated in large-scale prospective clinical investigations.
Hyperlactatemia: An Update on Postoperative Lactate
In patients with evidence of adequate perfusion, a type B component is often associated with a concomitant balanced (normal anion gap) metabolic acidosis and hyperglycemia. These patients will benefit from a more nuanced approach to their type B hyperlactatemia, as many will have a benign course and may be managed expectantly.