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Elevated Growth Differentiation Factor 15 Levels Predict Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) has emerged as a treatment of aortic stenosis in patients at high surgicalrisk. However, risk stratification in this elderly population is challenging, as patients at extreme risk might not benefit from TAVI.
Awake Extracorporeal Life Support and Physiotherapy in Adult Patients: A Systematic Review of the Literature
Awake ECLS strategy associated with physiotherapy is performed regardless of cannulation approach. Ambulation, as main objective, is achieved in almost half the population examined. Prospective studies are needed to evaluate safety and efficacy of physiotherapy during Awake ECLS, and suitable patient selection. Guidelines are required to identify appropriate assessment/evaluation tools for Awake ECLS patients monitoring.
Optimizing Cerebral Perfusion and Hemodynamics During Cardiopulmonary Bypass Through Cannula Design Combining In Silico, In Vitro And In Vivo Input
From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.
