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Bubbles in the bloodstream are not a normal condition - yet they remain a fact of cardiopulmonary bypass (CPB), having been extensively studied and documented since its inception some 50 years ago.
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The aim of this prospective randomised, controlled, double-blind study conducted in patients undergoing cardiac surgery was to assess the microcirculatory effects of landiolol given at a moderate dose to prevent POAF. We tested the hypothesis that landiolol could limit cardiopulmonary-bypass-induced microcirculatory abnormalities.
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