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We reviewed the pathophysiology of the inflammatory response to extracorporeal membrane oxygenation (ECMO), highlighting the complex interactions between arms of the innate immune response, the endothelium and coagulation.
TAVI procedure, in high risk patients with critical aortic stenosis, can be accomplished with low procedural mortality. The worst outcome affects particularly patients with renal insufficiency and previous coronary bypass. However, the long-term mortality remains high due to the poor baseline conditions, mainly related to co-morbidity and to the presence of residual post-procedural aortic insufficiency.