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Total Arterial Revascularization: A Superior Method of Cardiac Revascularization
No patient should be deprived of the benefits of total arterial revascularization allowed by the bilateral use of both internal thoracic arteries.
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Toll-like Receptor 9 and the Inflammatory Response to Surgical Trauma and Cardiopulmonary Bypass
CPB, surgical trauma and ischemic perfusion injury trigger the release of circulating mtDNA that activates TLR-9, in turn stimulating a release of IL-6. Therefore, TLR-9 antagonists may attenuate this response and may provide a future therapeutic target whereby the systemic inflammatory response to cardiac surgery may be manipulated to improve clinical outcomes.
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