Protamine Sulfate Shortage

Protamine Sulfate 10 mg/mL, American Pharmaceutical Partners (APP)
5 mL vials (NDC 63323-0229-05)
5 mL Novaplus vials (NDC 63323-0229-15)
25 mL vials (NDC 63323-0229-30)
25 mLNovaplus vials (NDC 63323-0229-35)

Reason for the Shortage

• APP has protamine on shortage due to increased demand.
  
• There are no other manufacturers of protamine sulfate.

Estimated Resupply Dates

• APP has protamine sulfate 10 mg/mL 5 mL and 25 mL vials on allocation.
  
• APP has 5 mL Novaplus vials available for direct order only because they have an expiration date of July, 2011. The 25 mL Novaplus vials are on back order and the company cannot estimate a release date.