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Hemoadsorption Eliminates Remdesivir from the Circulation: Implications for the Treatment Of COVID-19
Remdesivir and its main active metabolite GS‐441524 are rapidly eliminated from the perfusate by the CytoSorb® adsorber device in vitro. This should be considered in patients for whom both therapies are indicated, and simultaneous application should be avoided. In general, plasma levels of therapeutic drugs should be closely monitored under concurrent CytoSorb® therapy.
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Monitoring Activated Clotting Time for Combined Heparin and Aprotinin Application: An In Vitro Evaluation of a New Aprotinin-Insensitive Test Using SONOCLOT
new so-called 'aprotinin-insensitive' ACT test (SaiACT) has been developed for the SONOCLOT analyzer. In this study we evaluated and compared this new test for the SONOCLOT analyzer in vitro with an established kaolin-based ACT from HEMOCHRON (HkACT).
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Intra-Articular Injection of Photo-Activated Platelet-Rich Plasma in Patients with Knee Osteoarthritis: A Double-Blind, Randomized Controlled Pilot Study
This pilot study assessed the feasibility, safety and symptomatic and functional change following injections of photo-activated platelet-rich plasma (PA-PRP) compared to hyaluronic acid (HA) in people with knee osteoarthritis (OA).
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