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Role of Protein Kinase C- (PKC) in Isoflurane-Induced Cardioprotection
Although isoflurane preconditioning resulted in a reduction in infarct size at all concentrations used, the protection was mediated by phosphorylation and translocation of PKC only at 0.4 MAC.
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Late Occlusion of Drug-Eluting Stents Seen After Antiplatelet Therapy Halted
Even a year after placement of drug-eluting coronary stents, in-stent thrombosis may develop if antiplatelet therapy is discontinued, according to a research letter in the October 23rd issue of The Lancet.
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Hyperoxia During Cardiopulmonary Bypass Is Associated With Mortality in Infants Undergoing Cardiac Surgery
Hyperoxia during cardiopulmonary bypass was an independent risk factor for mortality and may be a modifiable risk factor. Furthermore, hyperoxia during cardiopulmonary bypass was associated with four-fold greater odds of mortality within 30 days of surgery.
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