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Accounting for the Relationship Between Per Diem Cost and LOS When Estimating Hospitalization Costs
Hospitalization costs in clinical trials are typically derived by multiplying the length of stay (LOS) by an average per-diem (PD) cost from external sources. This paper describes how to model the relationship between PD cost and LOS using flexible statistical modelling techniques.
Will High-Dose Heparin Affect Blood Loss and Inflammatory Response in Patients Undergoing Cardiopulmonary Bypass?
This small study showed a small increase of post-operative bleeding associated with higher heparin dosage in conjunction with cardiopulmonary bypass but did not demonstrate an effect of heparin on the inflammatory response to cardiopulmonary bypass.