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Update on Clinical Trials for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery
Effective therapeutic agents for the prevention and treatment of acute kidney injury (AKI) after cardiac surgery remain elusive despite the tremendous advances in surgical techniques, technology, and understanding of disease processes. Recent developments and their effect on the incidence of AKI after cardiac surgery are discussed.
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Toward an Artificial Endothelium: Development of Blood-Compatible Surfaces for Extracorporeal Life Support
Here, we describe clinically approved and new investigational biomaterial solutions for thrombosis, such as immobilized heparin, nitric oxide-functionalized polymers, “slippery” nonadhesive coatings, and surface endothelialization.
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