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We reviewed the pathophysiology of the inflammatory response to extracorporeal membrane oxygenation (ECMO), highlighting the complex interactions between arms of the innate immune response, the endothelium and coagulation.
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Impact of CytoSorb on Kinetics of Vancomycin and Bivalirudin in Critically ill Patients
CytoSorb is effective in mitigating the systemic inflammatory response and safe with respect to vancomycin and bivalirudin administration. These preliminary data further support the use of CytoSorb as adjunct therapy in critically ill patients.
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The Strong Ion Gap Predicts Mortality in Children Following Cardiopulmonary Bypass Surgery
Our study objectives were as follows: a) to determine the 24-hr profile of the strong ion gap following cardiopulmonary bypass surgery; and b) to compare the prognostic value in terms of intensive care unit mortality of this variable with blood lactate.
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