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Aprotinin Inhibits Proinflammatory Activation of Endothelial Cells by Thrombin Through the Protease-Activated Receptor 1
Here we have examined whether aprotinin inhibits endothelial protease-activated receptor 1 activation and resulting proinflammatory responses induced by thrombin.
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Managing the Coagulopathy Associated with Cardiopulmonary Bypass.
While challenging, the effective management of CPB‐associated coagulopathy can significantly improve patient outcomes.
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Thrombin Generation and Antithrombin Activity in Infants Undergoing Cardiopulmonary Bypass—An Exploratory Study
In pediatric patients <10 kg undergoing cardiac surgery with CPB, thrombin generation and AT activity decline and do not recover completely after transfusion of platelets and cryoprecipitate.
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