Comparison of Hollow-Fiber Membrane Oxygenators in Terms of Pressure Drop of the Membranes During Normothermic and Hypothermic Cardiopulmonary Bypass in Neonates

Using an idealized geometry of the aorta and its major branches and a peripherally inserted return cannula terminating in the iliac artery, computational fluid dynamic simulations were performed to (1) quantify perfusion as function of relative ECMO flow and (2) describe the watershed region produced by the collision of antegrade flow from the heart and retrograde ECMO flow.