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Modified Ultrafiltration Reduces Postoperative Blood Loss and Transfusions in Adult Cardiac Surgery: A Meta-Analysis of Randomized Controlled Trials
MUF is a safe and feasible option in adult cardiac patients, with significant benefits including improved postoperative haematocrit, as well as reduced postoperative chest tube bleeding, transfusion requirements and duration of ICU stay.
Dextran-Based Priming Solution during Cardiopulmonary Bypass Attenuates Renal Tubular Injury – A Secondary Analysis of Randomized Controlled Trial in Adult Cardiac Surgery Patients
In patients undergoing cardiac surgery with CPB, colloid-based priming solution (dextran 40) induced less renal tubular injury compared to a crystalloid-based priming solution. Whether a colloid-based priming solution will improve renal outcome in high-risk cardiac surgery, or not, needs to be evaluated in future studies on higher risk cardiac surgery patients.
Genome-Wide Association Study of Acute Kidney Injury after Coronary Bypass Graft Surgery Identifies Susceptibility Toci
Acute kidney injury (AKI) is a common, serious complication of cardiac surgery. Since prior studies have supported a genetic basis for postoperative AKI, we conducted a genome-wide association study (GWAS) for AKI following coronary bypass graft (CABG) surgery.