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Ex Vivo Perfusion of the Heart with an Aim to Increase Viable Hearts for Transplantation (EP Video)
The race is on to develop an affordable, hybridized ex vivo heart perfusion system in which load-independent biventricular contractility and contractile reserve can be measured (26:40 minutes).
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Tricuspid valve Endocarditis Following Central Venous Cannulation: The Increasing Problem of Catheter Related Infection
We report a case of tricuspid valve endocarditis, probably secondary to injury of the anterior tricuspid leaflet by the guide wire or the CVC that required open heart surgery with vegetectomy and repair of the tricuspid valve.
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Methylprednisolone Plasma Concentrations During Cardiac Surgery With Cardiopulmonary Bypass in Pediatric Patients
We report similar methylprednisolone plasma concentrations as earlier studies performed in children undergoing cardiopulmonary bypass, and we confirmed the large interindividual variability in achieved methylprednisolone plasma concentrations with weight-based methylprednisolone administration. A larger volume of distribution and a lower clearance of methylprednisolone for neonates were suggested. The half-life of methylprednisolone in our study was calculated to be longer than 6 h for neonates, 4.7 h for infants, 3.6 h for preschool children and 4.7 h for school children. The possible influence of treatment of pulmonary hypertension with sildenafil and temperature needs to be investigated further.
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