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Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery The FIBRES Randomized Clinical Trial
In patients undergoing cardiac surgery who develop clinically significant bleeding and hypofibrinogenemia after cardiopulmonary bypass, fibrinogen concentrate is noninferior to cryoprecipitate with regard to number of blood components transfused in a 24-hour period post bypass.
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Hyperglycemia, Hypoglycemia, and Glycemic Complexity Are Associated With Worse Outcomes After Surgery
We found that hypoglycemia (glucose <71 mg/dL) and hyperglycemia (glucose >140 mg/dL) were associated with increased risk of complications, whereas greater complexity of the glucose time series was associated with mortality.
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Altered Frontal White Matter Microstructure is Associated with Working Memory Impairments in Adolescents with Congenital Heart Disease: A Diffusion Tensor Imaging Study
Adolescence, which is a crucial period for prefrontal brain maturation, may offer a window of opportunity for intervention in order to support the maturation of frontal brain regions and therefore improve higher order cognitive function in patients with CHD.
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