Which Factors Have a Great Impact on Coagulopathy and Hemostatic Impairment after Cardiopulmonary Bypass in Cardiovascular Surgery? An Analysis Based on Rotational Thromboelastometry

Findings from this systematic review and meta-analysis of 216 studies suggested that intravenous TXA, irrespective of dosing, is not associated with increased risk of any TE. These results help clarify the incidence of adverse events associated with administration of intravenous TXA and suggest that TXA is safe for use with undetermined utility for patients receiving neurological care.