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Trends and Emerging Technologies in Extracorporeal Life Support: Results of the 2006 ECLS Survey
This article presents our 2006 ECLS survey results and discusses emerging technologies and management topics new to the ECLS arena.
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Non-Pulsatile Blood Flow is Associated with Enhanced Cerebrovascular Carbon Dioxide Reactivity and an Attenuated Relationship Between Cerebral Blood Flow and Regional Brain Oxygenation
Non-pulsatile perfusion is associated with enhanced cerebrovascular CVR resulting in greater relative decreases of cerebral blood flow during hypocapnia.
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Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) offers therapeutic options in refractory respiratory and/or cardiac failure. Systemic anticoagulation with heparin is routinely administered. However, in patients with heparin-induced thrombocytopenia or heparin resistance, the direct thrombin inhibitor bivalirudin is a valid option and has been increasingly used for ECMO anticoagulation. We aimed at evaluating its safety and its optimal dosing for ECMO.
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