Tug of War: Blood Management Safety (Video)
World's Largest Resource for Cardiovascular Perfusion
Andrea Peters discusses the various blood management strategies employed at St. Francis Hospital (28:26 minutes).
Compared with nondiabetic patients, there was no significant upregulation of FOXO3α in diabetic patients, which could possibly explain the lack of upregulation of the autophagy process after CPB. FOXO3α could potentially serve as a therapeutic target to improve cellular homeostasis.
Cardiothoracic surgical leadership recently challenged the surgical community to achieve an operative mortality rate of 1.0% for the performance of isolated coronary artery bypass grafting (CABG). The purpose of our study was to identify a patient population in which this operative mortality goal is achievable relative to the estimated operative risk.