Trends and Outcomes of Red Blood Cell Transfusion in Patients Undergoing Transcatheter Aortic Valve Replacement in the United States

To address the unmet need for enhancing the thromboresistance of these devices to extend their long term use, we developed a universal predictive methodology entitled Device Thrombogenicity Emulation (DTE) that facilitates optimizing the thrombogenic performance of any MCS device--ideally to a level that may obviate the need for mandatory anticoagulation.