Central Venous O₂ Saturation and Venous-to-Arterial CO₂ Difference as Complementary Tools for Goal-Directed Therapy During High-Risk Surgery
We tested the hypothesis that central venous-to-arterial carbon dioxide difference (P(cv-a)CO2), a global index of tissue perfusion, could be used as a complementary tool to ScvO2 for goal-directed fluid therapy (GDT) to identify persistent low flow after optimization of preload has been achieved by fluid loading during high-risk surgery.
