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Cardiopulmonary Bypass, Hemolysis, and Nitroprusside-Induced Cyanide Production
Cyanide toxicity is a complication of sodium nitroprusside administration. Cardiac surgery may increase the risk of cyanide toxicity, because hemolysis during cardiopulmonary bypass (CPB) may catalyze the release of free cyanide from sodium nitroprusside.
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Increased Circulating Levels of Neutrophil Extracellular Traps During Cardiopulmonary Bypass
Circulating NETs measurements increases during cardiac surgery with postsurgical levels proportional to CPB duration. The clinical significance of NETs production during cardiac surgery should be further investigated.
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Del Nido cardioplegia in low risk adults undergoing first time coronary artery bypass surgery.
Single-dose del Nido cardioplegia has been used in the pediatric population for many years. Only a small amount of data exists about its use in adult cardiac surgery. We sought to compare the outcomes of all patients undergoing coronary artery bypass, using our 4:1 blood cardioplegia versus single-dose 1:4 del Nido cardioplegia, at our institution.
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