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The Kinetics of Plasmin Inhibition by Aprotinin in Vivo
The rise in plasmin generation and fibrin degradation that occurs during standard CPB is suppressed by the addition of aprotinin, which returns the patient to near baseline fibrin degradation rates during CPB.
Thermal Distribution, Physiological Effects and Toxicities of Extracorporeally Induced Whole‐Body Hyperthermia in a Pig Model
Fast induction of eWBH with homogenous thermal distribution is feasible in pigs using the Vithèr WBH device. Severe hemodynamic disturbances, rhabdomyolysis, and hyperkalemia were observed.
High‐Dose Nitroglycerin Administered During Rewarming Preserves Erythrocyte Deformability in Cardiac Surgery with Cardiopulmonary Bypass
High‐dose nitroglycerin administered during cardiopulmonary bypass improves erythrocyte deformability through activating phosphorylation of aquaporin 1, vasodilator‐stimulated phosphoprotein, and focal adhesion kinase in erythrocytes.