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Effects of Haemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
The aim of our present study was to evaluate the ability of antioxidant therapy with mannitol or haemofiltration during CPB to modulate this immunosuppression after CPB.
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Newborn is First to Use Artificial Lung
A newborn baby from Michigan is being kept alive at St. Louis Children’s Hospital with an artificial lung, the first time such a device has been used as a bridge to transplant for a child this small.
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Acute Respiratory Distress Syndrome in the Perioperative Period of Cardiac Surgery: Predictors, Diagnosis, Prognosis, Management Options, and Future Directions
More research in the setting of ARDS after cardiac surgery is needed at multiple levels (risk factors, diagnosis, treatment options). Prevention of lung injury appears to be of the utmost importance, and a better characterization of the risk factors is needed. Avoiding excessive perioperative transfusions and the optimization of ventilation and hemodynamics seem to be the most modifiable risk factors. In patients who develop ARDS after cardiac surgery, extracorporeal techniques may represent a valid choice in experienced hands. The use of NMBAs, prone positioning, and iNO can be considered on a case-by-case basis, whereas aggressive lung recruitment and oscillatory ventilation probably should be avoided.
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