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Updates on Coagulation Management in Cardiac Surgery
Perioperative coagulopathy is regularly observed in patients undergoing cardiovascular surgery and is associated with massive bleeding, increased need for blood products transfusion, and re-exploration for surgical hemostasis.
Preservation Solution Supplemented with Biliverdin Prevents Lung Cold Ischaemia/Reperfusion Injury
This study demonstrates that the exposure of the lung grafts to BV during cold storage can impart potent cytoprotective effects to lung cold ischaemia/reperfusion injury and significantly improve the lung graft function following extended cold preservation and transplantation by the mechanism of a reduction in oxidative injury and following inflammatory events.
A Failure Mode Effect Analysis on Extracorporeal Circuits for Cardiopulmonary Bypass
Although many refinements in perfusion methodology and devices have been made, extracorporeal circulation remains a contributor to neurological complications, bleeding coagulopathies, use of blood products, as well as systemic inflammatory response.