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Dual Versus Single Anti-platelet Therapy in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-analysis
Although dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is a widely accepted strategy in patients undergoing transcatheter aortic valve replacement (TAVR), this approach is not evidence based. We therefore sought to systematically review the currentevidence for this practice in terms of 30-day outcome looking at stroke, MI, bleeding, and death.
Pharmacokinetic Model for Cefuroxime Dosing During Cardiac Surgery Under Cardiopulmonary Bypass
Our model yielded an optimized CXM dosing regimen adapted to bodyweight and renal function, and sustaining therapeutic concentrations consistent with each desired threshold. The optimal target concentration and necessary duration of its maintenance in cardiac surgery still remain unclear.
Increased Long-Term Mortality with Plasma Transfusion after Coronary Artery Bypass Surgery
This study explores the relation between the transfusion of different blood components and long-term mortality.