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Pharmacokinetic Model for Cefuroxime Dosing During Cardiac Surgery Under Cardiopulmonary Bypass
Our model yielded an optimized CXM dosing regimen adapted to bodyweight and renal function, and sustaining therapeutic concentrations consistent with each desired threshold. The optimal target concentration and necessary duration of its maintenance in cardiac surgery still remain unclear.
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Heparin-Coated Adult ECMO vs. Ventricular Assist Devices: A Decision Analysis Modeling Approach
This model suggests that patients should be supported on heparincoated ECMO for 2–3 days to evaluate their potential for recovery before instituting more expensive ventricular assist devices.
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Reliability of the Minto Model for Target-Controlled Infusion of Remifentanil during Cardiac Surgery with Cardiopulmonary Bypass
The Minto model accurately predicts plasma remifentanil concentrations during cardiac surgery with CPB.
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