Fibrinogen Concentrate Reduces Intraoperative Bleeding when used as First-Line Hemostatic Therapy During Major Aortic Replacement Surgery: Results from a Randomized, Placebo-Controlled Trial
We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing major aortic surgery.
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