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Fondaparinux as an Alternative Anticoagulant in Heparin-Induced Thrombocytopenia in the Patient with a Ventricular Assist Device
We present a patient who, after a heart transplant, and the need for a ventricular assist device, required anticoagulation. The patient developed heparin-induced thrombocytopenia.
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Evaluation of Autologous Retransfusion from A Closed Suction Drainage System for Patient Blood Management in Elective Total Hip and Knee Replacement: A Two Cohort Study
Our study questions the effectiveness of postoperative autotransfusion as part of a patient blood management programme. In addition, the obvious signs of inflammatory reactions and coagulation activation raise safety concerns.
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Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance
During routine CPB, high-dose unfractionated heparin (UFH) prevents consumptive coagulopathy and the formation of thrombi within the CPB circuit and the patient's circulation. Prior treatment with andexanet alfa can pose difficulties in achieving adequate anticoagulation during CPB with UFH. The administration of antithrombin, in combination with UFH, may overcome these difficulties.
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