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Tranexamic Acid Attenuates Inflammatory Response in Cardiopulmonary Bypass Surgery Through Blockade of Fibrinolysis: A Case Control Study Followed by a Randomized Double-Blind Controlled Trial
Tranexamic acid (TA) reduces fibrinolysis and blood loss after cardiopulmonary bypass (CPB). However, its effects on IR and vasoplegic shock (VS) are not well known and this was the main objective of this study.
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Low Mean Arterial Pressure During Cardiopulmonary Bypass and the Risk of Acute Kidney Injury: A Propensity Score Matched Observational Study
Low MAP periods during CPB are associated with an increased occurrence of post-operative AKI, leading to 1) higher creatinine levels; 2) decreased GFR and 3) longer ICU and ward lengths of stay. Both consecutive and cumulative periods of low MAP are associated with an increased risk of AKI. MAP appears to be an important contributor to post-operative AKI and should be carefully managed during CPB. Further studies must address if MAP variations lead to definitive and long-term consequences.
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While Heart Disease Will Surge,<br />Safety in Hospitals Becomes Better
By Luc Puis There is bad news with good news and good news with bad news, just to show that there are […]
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