The Efficacy and Safety of Prophylactic Corticosteroids for the Prevention of Adverse Outcomes in Patients Undergoing Heart Surgery Using Cardiopulmonary Bypass: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
In the present meta-analysis of 62 RCTs (16 457 patients), including the 2 major RCTs (SIRS and DECS trials: 12 001 patients), we found that prophylactic corticosteroids in cardiac surgery did not reduce mortality.