Cerebrovascular Autoregulation and Arterial Carbon Dioxide in Patients with Acute Respiratory Distress Syndrome: A Prospective Observational Cohort Study
Our results suggest that moderate permissive hypercapnia during the acute phase of ARDS has no adverse effect on cerebrovascular autoregulation and may be tolerated to a certain extent to achieve low tidal volumes. In contrast, episodes of hypocapnia may compromise cerebral blood flow regulation.