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Geographic Variability in Potentially Discretionary Red Blood Cell Transfusions After Coronary Artery Bypass Graft Surgery
A number of established regional quality improvement collaboratives have partnered to assess and improve care across their regions under the umbrella of the Cardiac Surgery Quality Improvement (IMPROVE) Network. The first effort of the IMPROVE Network has been to assess regional differences in potentially discretionary transfusions (<3 units red blood cells [RBCs]).
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Heparin-Coated Cardiopulmonary Bypass Circuits Selectively Deplete the Pattern Recognition Molecule Ficolin-2 of the Lectin Complement Pathway in vivo
These findings may have implications for the postoperative susceptibility to infections
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Leukocyte Effects of C5a-Receptor Blockade During Simulated Extracorporeal Circulation
We hypothesized that a human C5a receptor antagonist would specifically inhibit the inflammatory response of neutrophils to simulated extracorporeal circulation, while preserving the C5b-9 pathway for innate immunity.
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