Balanced Regulation of mRNA Production for Fas and Fas Ligand in Lymphocytes From Centenarians. How the Immune System Starts Its Second Century
Lymphocytes from centenarians are able to balance the production of proapoptotic (mFas and FasL) and antiapoptotic (sFas) molecules, whose proportions are likely crucial for the well-preserved immune functionality at the extreme limits of human life.