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Blood Conservation Strategies in Cardiac Valve Replacement: A Retrospective Analysis of 1645 Patients
We aimed to evaluate whether blood conservation strategies including intraoperative autologous donation (IAD) could reduce perioperative blood transfusion for patients undergoing cardiac valve replacement including mitral valve replacement, aortic valve replacement (AVR), and double valve replacement (DVR).
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Clinical and Surgical Strategies for Avoiding or Reducing Allogeneic Blood Transfusions
Blood transfusions have still been used as a standard therapy to treat severe anemia. Current evidences point to both excessive allogeneic blood consumption and decreased donations, which result in reduced stocks in blood banks.
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Dynamic Responses of Renal Oxygenation at the Onset of Cardiopulmonary Bypass in Sheep and Man
Renal medullary hypoxia is an early event during CPB. It starts to develop even before CPB, presumably due to a pressure-dependent decrease in renal blood flow. Medullary hypoxia during CPB appears to be promoted by hypotension and is not ameliorated by increasing blood hemoglobin concentration.
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